Principal Scientist, Molecular Design

A company is looking for a Principal Scientist, Molecular Design. Key Responsibilities Lead multiple pipeline programs through hit exploration and hit-to-lead, setting strategies for progression into lead optimization Manage multiple direct reports leading efforts on pipeline projects Design small molecules using high-throughput computational tools and collaborate with various teams to develop generative design tools Required Qualifications BS/MS/Ph.D in computational, organic, or medicinal chemistry, or a related field 7 or more years of experience as a computational or medicinal chemist in industry Publications and patents demonstrating design contributions Experience with ligand-based and structure-based methods for small molecule design Familiarity with Python and RDKit

May 10, 2025 - 00:44
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Principal Scientist, Molecular Design
A company is looking for a Principal Scientist, Molecular Design. Key Responsibilities Lead multiple pipeline programs through hit exploration and hit-to-lead, setting strategies for progression into lead optimization Manage multiple direct reports leading efforts on pipeline projects Design small molecules using high-throughput computational tools and collaborate with various teams to develop generative design tools Required Qualifications BS/MS/Ph.D in computational, organic, or medicinal chemistry, or a related field 7 or more years of experience as a computational or medicinal chemist in industry Publications and patents demonstrating design contributions Experience with ligand-based and structure-based methods for small molecule design Familiarity with Python and RDKit